42 Awardee Talk: Utilizing Genomics to Understand Skeletal and Mammary Development in Pigs

نویسندگان

چکیده

Abstract Embryonic development in mammals is strictly controlled. Yet, anomalies regularly occur within certain species. The pig one of few species where variation vertebra numbers frequently occurs. Domesticated lines typically have a greater number thoracic and/or lumbar than the vertebrae most mammals. Number functional teats also variable swine and deviation from bilateral symmetry common. Positive genetic correlations between these two traits been reported gene variant vertnin affects both traits. To further investigate correlation teat counts numbers, genomewide association study was conducted using 5,939 genotyped animals USMARC population representative commercial swine. All were with four different Illumina-based BeadChips. Genotypes imputed for 71,634 markers pedigrees findhap. gEBV estimated marker effects backsolved WOMBAT. region had greatest significant associations all analyzed. However, there no other that overlapped number. Correlation among ~0.21. if SNP surrounding removed, dropped to 0.14, while ~0.90. Genomic heritabilities 0.36 0.78. Analyses GRM only included heritabilites 0.05 0.48, indicating described majority rib but much less Genetic phenotypic weight near zero. A positive birth existed despite low negative correlation. USDA an equal opportunity employer.

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ژورنال

عنوان ژورنال: Journal of Animal Science

سال: 2022

ISSN: ['0021-8812', '1525-3163', '1525-3015', '1544-7847']

DOI: https://doi.org/10.1093/jas/skac247.019